Disability Predicts Longitudinal Depression in People with Multiple Sclerosis
Objectives: To evaluate the predictive value of disability data on depression over time.
Methods: Participants (N = 121) were recruited from an outpatient clinic at a large medical center in New Jersey. Longitudinal data were collected as part of an ongoing research project. Participants completed a Beck Depression Inventory-II (BDI-II), Incapacity Status Scale (ISS), and a demographic questionnaire. Linear regressions were used to assess the ISS as a predictor of BDI-II score at baseline and follow-up, and of change in BDI-II over time.
Results: ISS scores positively predicted BDI scores at baseline (β = .429, p < .001) and follow-up (β = .380, p < .001), and change in BDI-II score over time (β = .272 , p = .003).
Conclusions: Higher levels of disability predict greater depression in individuals with MS, both cross-sectionally and longitudinally.