SX10
The Influence of Bowel Dysfunction and Depression on Illness Intrusiveness in Multiple Sclerosis Using a Moderator Model
Thursday, May 29, 2014
Trinity Exhibit Hall
Andrew S Castiglione, B.S.
,
Ross University School of Medicine, North Brunswick, NJ
Elizabeth S Gromisch, M.A.
,
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY
Stacey Snyder, M.A.
,
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY
Vance Zemon, Ph.D.
,
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY
Laura C Schairer, M.A.
,
Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY
Mary Ann Picone, M.D.
,
Holy Name Medical Center, Teaneck, NJ
Eileen Farrell, Ph.D.
,
New York University Comprehensive Epilepsy Center, New York, NY
Meghan Beier, PhD
,
Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA
Sonya Kim, Ph.D.
,
Holy Name Medical Center, Teaneck, NJ
Frederick W Foley, Ph.D.
,
Holy Name Medical Center, Teaneck, NJ
PDF
Background: Multiple sclerosis (MS) is an autoimmune disorder affecting the central nervous system. Bowel dysfunction can occur, with constipation and fecal incontinence as the two most frequently reported issues, with the prevalence rates at 35-54% and 29-51%, respectively. Both gastrointestinal issues can cause physical and social problems, thus potentially affecting MS patients’ quality of life (QoL). One way of measuring QoL in MS is with the Illness Intrusiveness Ratings Scale (IIRS), a 13-item questionnaire that measures several different domains, including relationships and instrumental tasks of daily living.
Objectives: We hypothesize that by using depression, as measured by the Beck Depression Scale (BDI), as a moderator, bowel dysfunction, as measured by the Incapacity Status Scale (ISS), will be related to perceived illness intrusiveness.
Methods: Data is analyzed with a moderator model, using Hayes' PROCESS Conceptual Model 1.
Results: Participants’ (N= 213) bowel dysfunction ranges from severe to none, with the majority having mild to none. The model is significant (p <0.0005), as is the relationship between illness intrusiveness and depression (p <0.0005). The relationship between bowel dysfunction and illness intrusiveness is not significant (p = 0.1237), and the relationship between illness intrusiveness and the interaction of bowel dysfunction and depression is nearly significant (p = 0.0514), suggesting a trend.
Conclusions: As our participants have more mild bowel dysfunction, we hypothesize that MS patients with more severe bowel dysfunction may report higher levels of illness intrusiveness.
