Non-imaging Biomarkers

Tuesday, October 26, 2021: 5:00 PM-7:00 PM
Exhibit Hall (Rosen Shingle Creek)
The Effect of Evobrutinib, a Bruton’s Tyrosine Kinase Inhibitor, on Blood Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis
Jens Kuhle, MD, PhD, University Hospital Basel, and University of Basel; Ludwig Kappos, MD, University Hospital Basel, and University of Basel; Xavier Montalban, MD, PhD, Hospital Universitario Vall d'Hebron; Ying Li, MS, Global Clinical Development Center; Karthinathan Thangavelu, PhD, Global Clinical Development Center; Yann Hyvert, PhD, Merck KGaA; Davorka Tomic, PhD, Merck KGaA

Concentration of Evobrutinib, a Bruton’s Tyrosine Kinase Inhibitor, in Cerebrospinal Fluid during Treatment of Patients with Relapsing Multiple Sclerosis in a Phase 2 Study
Karolina Piasecka-Stryczynska, PhD, Poznan University of Medical Sciences; Konrad Rejdak, MD, PhD, Medical University of Lublin; Martin Dyroff, PhD, EMD Serono Research & Development Institute, Inc (an affiliate of Merck KGaA, Darmstadt, Germany); Yann Hyvert, PhD, Merck KGaA; Kristina Holmberg, PhD, EMD Serono Research & Development Institute, Inc (an affiliate of Merck KGaA, Darmstadt, Germany); Matthew Mandel, MD, EMD Serono Research & Development Institute, Inc (an affiliate of Merck KGaA, Darmstadt, Germany); Carolina Cunha, PhD, PharmD, EMD Serono Research & Development Institute, Inc (an affiliate of Merck KGaA, Darmstadt, Germany); David Mitchell, PhD, Nuventra Inc.; Emily C. Martin, PhD, EMD Serono Research & Development Institute, Inc (an affiliate of Merck KGaA, Darmstadt, Germany); Xavier Montalban, MD, PhD, Hospital Universitari Vall d’Hebron

Combinatorial Analysis of Plasma and DNA Methylation Biomarkers in African American Patients with Multiple Sclerosis
Lindsay Clark, PhD, University of Illinois; Mark Band, PhD, University of Illinois; Jason P. Mendoza, PhD, Biogen; Linda Piccinini, PhD, Biogen; Michael D Carrithers, MD, PhD, University of Illinois College of Medicine, Jesse Brown Veterans Hospital

Predicting Stress Levels and Response to a Self-Management Program Using Participant Demographic, Clinical, and Biomarker Data: A Secondary Analysis
Nico Osier, PhD, RN, The University of Texas at Austin, Dell Medical School; Alexa Stuifbergen, PhD, RN, FAAN, The University of Texas at Austin; Sawyer Stubbs, BS, University of Texas at Austin; Tapasvini Paralkar, BS, University of Texas at Austin
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Non-Right-Handedness May be Associated with More Severe Multiple Sclerosis
Ruth E Propper, Ph.D., Montclair State University; Melissa Villafana, B.A., Montclair State University; Glenn R Wylie, Ph.D., Kessler Foundation

Validating the Clinical Usefulness of the Timed 25-Foot Walk in MS in Routine Clinical Practice
Sage T Hewitt, B.S., USF Health Morsani College of Medicine; Derrick Robertson, MD, University of South Florida; Angela Aungst, MPH, Multiple Sclerosis Division Department of Neurology University of South Florida; Christopher James, B.S., USF Health Morsani College of Medicine

Cerebrospinal Fluid Protein Is Higher in Males with Multiple Sclerosis: Results from an International Multicenter Cohort
Sam I Hooshmand, DO, Medical College of Wisconsin; Khalid El-Salem, MD, Jordan University of Science and Technology; Suha Agaileh, MD, Jordan University of Science and Technology; Ahmed Z Obeidat, MD, PhD, Medical College of Wisconsin
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