DX
Disease Modification

Thursday, June 2, 2016: 6:15 PM-8:15 PM
Exhibit Hall
Efficacy of Teriflunomide in MS Patients with a Primary Presentation of Optic Neuritis: A Subgroup Analysis of the Phase 3 TOPIC Study
Aaron E Miller, MD, Icahn School of Medicine at Mount Sinai; Jiwon Oh, MD, St. Michael's Hospital; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Philippe Truffinet, MD, Genzyme, a Sanofi company; Steve Cavalier, MD, Genzyme, a Sanofi company; David Rog, MD, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust
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Clinical Outcomes in Patients with Faster Advancing MS Treated with Teriflunomide in TEMSO and TOWER
Aaron E Miller, MD, Icahn School of Medicine at Mount Sinai; Ludwig Kappos, MD, University Hospital Basel; Jiwon Oh, MD, St. Michael's Hospital; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Pascal Rufi, MD, Genzyme, a Sanofi company; Steve Cavalier, MD, Genzyme, a Sanofi company; Philippe Truffinet, MD, Genzyme, a Sanofi company; Giancarlo Comi, MD, University Vita-Salute San Raffaele
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Effects of Induced Depression on the Animal Model of Multiple Sclerosis: An Overlooked Disability
Amal Fuad Almahroos, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Zahra Almosawi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Hawra Alalwan, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Reem Abdulla, Bsc, College of Medicine and Medical Sciences, Arabian Gulf University; Fajer Alammadi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Ahmed Al-Mahrezi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Ahmmed Almubarak, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Ayman Mohamed, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Amer Kamal, Professor, College of Medicine and Medical Sciences, Arabian Gulf University
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Effect of Ocrelizumab on Humoral Immunity Markers in the Phase III, Double-Blind, Double-Dummy, IFNß-1a–Controlled OPERA I and OPERA II Studies
Amit Bar-Or, MD, FRCPC, McGill University; Douglas L Arnold, MD, McGill University; Giancarlo Comi, MD, University Vita-Salute San Raffaele; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Heinrich-Heine-University Düsseldorf; Stephen L Hauser, MD, University of California; Fred Lublin, MD, Icahn School of Medicine at Mount Sinai; Krzysztof Selmaj, MD, PhD, Medical University of Lodz; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Peter Chin, MD, Genentech, Inc.; Paulo Fontoura, MD, PhD, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Gaelle Klingelschmitt, MSc, F. Hoffmann-La Roche Ltd.; Donna Masterman, MD, Genentech, Inc.; Ludwig Kappos, MD, PhD, University Hospital Basel; Ashley J Porter, PhD, Articulate Science
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Real-World Outpatient Resource Use of Patients with Multiple Sclerosis Newly Initiating Subcutaneous Interferon ß-1a vs Oral Disease-Modifying Drugs
Chris M Kozma, PhD, CK Consulting Associates, LLC; Frederick Munschauer, MD, EMD Serono, Inc.; Amy L Phillips, PharmD, EMD Serono, Inc.; Michele Springer, BA, Caudex
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Cost of Patients with Multiple Sclerosis Newly Initiating Subcutaneous Interferon ß-1a Vs Oral Disease-Modifying Drugs – a Real-World Assessment
Chris M Kozma, PhD, CK Consulting Associates, LLC; Frederick Munschauer, MD, EMD Serono, Inc.; Amy L Phillips, PharmD, EMD Serono, Inc.; Michele Springer, BA, Caudex
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Comparison of Costs and Health Resource Utilization in Multiple Sclerosis Patients Treated with Disease-Modifying Therapies
Jacqueline Nicholas, MD, MPH, Novartis Pharmaceutical Corporation; Aaron Boster, MD, OhioHealth Neurological Physicians; Wei-Shi Yeh, PhD, Biogen; Robert Garland, MS, Biogen; Monica A Fay, PharmD, Biogen; Ravi Iyer, PhD, Biogen; Andrew Lee, PhD, Biogen; Ming-Yi Huang, PhD, Biogen; Jim B Lewin, PharmD, Biogen
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≥4 Active T2 Lesions at 6 Months Predicts Future Relapse/Disability in Patients with RMS on Placebo but Not IFN ß-1a SC tiw: Post Hoc PRISMS Analyses
Anthony Traboulsee, MD, FRCPC, University of British Columbia; Regina Berkovich, MD, PhD, University of Southern California; Hao Zhang, PhD, EMD Serono, Inc.; Fernando Dangond, MD, FAAN, MBA, EMD Serono, Inc.; David Li, MD, University of British Columbia; Michele Springer, BA, Caudex
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Patients with Highly Active RRMS Despite Prior Therapy Show Durable Improvement with Alemtuzumab over 5 Years
Barry A Singer, MD, The MS Center for Innovations in Care, Missouri Baptist Medical Center; Stephen Krieger, MD, Icahn School of Medicine, Corinne Goldsmith Dickinson Center for Multiple Sclerosis; Regina Berkovich, MD, Keck School of Medicine, University of Southern California; Mark S Freedman, MD, University of Ottawa and the Ottawa Hospital Research Institute; David H Margolin, MD, PhD, Genzyme, a Sanofi company; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Aaron Boster, MD, OhioHealth Neurological Physicians
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Delayed-Release Dimethyl Fumarate Does Not Adversely Affect the Pharmacokinetics of a Commonly Used Oral Contraceptive: A Drug-Drug Interaction Study
Bing Zhu, MD, PhD, Biogen; Karin Galil, MD, MPH, Biogen; Ivan Nestorov, PhD, Biogen; Guolin Zhao, PhD, Biogen; Venkata Meka, MD, Biogen; Jeanelle Kam, MD, CPI, Covance Clinical Research Unit; Sarah I. Sheikh, MD, Biogen; Jim B Lewin, PharmD, Biogen
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Disease Activity Is Associated with Non-Adherence in Dimethyl Fumarate Compared to Fingolimod in Clinical Practice
Carrie M Hersh, DO, MS, Cleveland Clinic; Samuel Cohn, MD, Cleveland Clinic; Claire Hara-Cleaver, CNP, Cleveland Clinic; Robert Bermel, MD, Cleveland Clinic; Robert J Fox, MD, FAAN, Cleveland Clinic; Jeffrey A Cohen, MD, Cleveland Clinic; Daniel Ontaneda, MD, Cleveland Clinic; Carrie M Hersh, DO, MS, Cleveland Clinic

Evaluating Effect of Dimethyl Fumarate on Leukocytes Among Caucasian-, African- and Hispanic-American Patients with Multiple Sclerosis (MS)
Carrie L Sammarco, DNP, FNP-C, MSCN, NYU Langone; Lana Zhovtis Ryerson, MD, New York State Multiple Sclerosis Consortium; Lisa Laing, BSN, RN, MSCN, NYU Langone
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Relapses in MS Patients Treated with DMF with No Variation in Lymphocyte Counts
Cecilie Fjeldstad, PhD, Oklahoma Medical Research Foundation; Tania Reyna, MD, Oklahoma Medical Research Foundation; Jennifer Smith, PA, Oklahoma Medical Research Foundation; Tony Sharp, PA, Oklahoma Medical Research Foundation; Gabriel Pardo, MD, Oklahoma Medical Research Foundation

A Comparative Analysis of Lymphocyte Subpopulations in Patients on Natalizumab, Fingolimod, and Dimethyl Fumarate
Christopher M Perrone, MD, University of Pennsylvania; Eric Williamson, MD, University of Pennsylvania; Christopher M Perrone, MD, University of Pennsylvania; Eric Williamson, MD, University of Pennsylvania
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SIRT1 as a Potential Marker of Disease Activity and Response to Treatment with Glatiramer Acetate in Multiple Sclerosis
Daniel Hewes, B.S., University of Maryland School of Medicine; Adam Kruszewski, B.S., University of Maryland School of Medicine; Dallas Boodhoo, B.S., University of Maryland School of Medicine; Alexandru Tatomir, M.D., University of Maryland School of Medicine; Vinh Nguyen, D.D.S., University of Maryland School of Medicine; Gautam K Rao, B.S., University of Maryland School of Medicine; Walter Royal III, M.D., Veterans Administration Multiple Sclerosis Center of Excellence; Christopher T Bever Jr., M.D., M.B.A., University of Maryland School of Medicine; Violeta Rus, M.D., Ph.D, University of Maryland School of Medicine; Horea Rus, M.D., Ph.D., Veterans Administration Multiple Sclerosis Center of Excellence
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RRMS Patients with an Inadequate Response to a Prior Therapy Demonstrate Slowing of Brain Volume Loss over 5 Years Following Alemtuzumab Treatment
Daniel Pelletier, MD, University of Southern California; Gavin Giovannoni, MBBCh, PhD, Queen Mary University London, Barts and The London School of Medicine; Douglas L Arnold, MD, McGill University; Sven Schippling, MD, University Hospital Zurich and University of Zurich; David H Margolin, MD, PhD, Genzyme, a Sanofi company; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Tina Walsh, n/a, Evidence Scientific
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Real-World Fingolimod First-Dose Effects in Patients with Hypertension, Cardiac Conditions and/or Receiving Selective Serotonin-Reuptake Inhibitors
Daniel Wynn, MD, Consultants in Neurology MS Center; Chris Laganke, MD, North Central Neurology Associates; Lesley Schofield, PhD, Novartis Pharmaceuticals Corporation; Xiangyi Meng, PhD, Novartis Pharmaceuticals Corporation; Nadia Tenenbaum, MD, Novartis Pharmaceuticals Corporation; Jeremy Bright, PhD, Oxford Pharmagenesis; Terence Smith, PhD, Oxford Pharmagenesis
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Interferon ß-1a SC tiw Reduces Cumulative MRI Lesions over 24 Months in Patients with Relapsing Multiple Sclerosis: Post Hoc Analyses of PRISMS Data
David Li, MD, FRCPC, University of British Columbia; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Eric Williamson, MD, University of Pennsylvania; Hao Zhang, PhD, EMD Serono, Inc.; Fernando Dangond, MD, FAAN, MBA, EMD Serono, Inc.; Michele Springer, BA, Caudex
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Can Fingolimod Reduce T1 Hypointense and Gadolium Enhancing Lesions in Hispanic MS Patients
Eduardo R Estades, MD, San Juan MS Center; Angel Chinea, MD, San Juan Multiple Sclerosis Center; Yatzka G Hernandez Silvestrini, MD, San Juan MS Center; Ivonne Vicente, MD, San Juan Multiple Sclerosis Center; Cristina Rubi, BS, San Juan Multiple Sclerosis Center; Kenneth Stein, MD, San Juan MRI; Eduardo R Estades, MD, San Juan MS Center; Angel Chinea, MD, San Juan Multiple Sclerosis Center
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No Evidence of Disease Activity for 4 Years Following 2 Courses of Alemtuzumab and No Further Treatment: Long-Term Responders from Care-MS II
Edward J. Fox, MD, PhD, Central Texas Neurology Consultants; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Heinrich-Heine-University Düsseldorf; Eva Havrdova, MD, PhD, Charles University in Prague; Brian Steingo, MD, Fort Lauderdale Multiple Sclerosis Center; David H Margolin, MD, PhD, Genzyme, a Sanofi company; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Gavin Giovannoni, MBBCh, PhD, Queen Mary University London, Barts and The London School of Medicine
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Correlation of Clinical, MRI, and OCT Outcomes in the 11-Year Follow up from Benefit: Benefit 11
Edward J Fox, MD, Central Texas Neurology Consultants; Gilles Edan, MD, CHU Hopital Pontchaillou; Mark S Freedman, MD, University of Ottawa and Ottawa Hospital Research Institute; Xavier Montalban, MD, PhD, Hospital Universitari Vall d’Hebron; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Department of Neurology, Heinrich-Heine Universität; Bernhard Hemmer, MD, Munich Cluster for Systems Neurology (SyNergy); Frederik Barkhof, MD, PhD, VU University Medical Center; Sven Schippling, MD, University Hospital Zurich; Frederick W Foley, Ph.D., School of Psychology, Yeshiva University; Iris-Katharina Penner, PD, COGITO Center for Applied Neurocognition and Neuropsychological Research; Ralf Koelbach, MSc, PAREXEL International; Dirk Pleimes, MD, Myelo Therapeutics GmbH; Gustavo Suarez, MD, Bayer HealthCare Pharmaceuticals; Eva-Maria Wicklein, MD, Bayer Pharma AG; Ludwig Kappos, MD, PhD, Neurology, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel; Beth Gates, BA, Precept Medical Communications; Robert Ristuccia, PhD, Precept Medical Communications
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Efficacy and Tolerability of Oral Disease Modifying Therapies in Clinical Practice
Erin E Longbrake, MD, PhD, Washington University School of Medicine; Anne H Cross, MD, Washington University School of Medicine; Amber Salter, PhD, Washington University in St. Louis; Erin E Longbrake, MD, PhD, Washington University School of Medicine
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Risk Factors for Lymphopenia in Patients with Relapsing Remitting Multiple Sclerosis Treated with Dimethyl Fumarate
Fabian Sierra Morales, MD, Beth Israel Deaconess Medical Center; Igor Koralnik, MD, Beth Israel Deaconess Medical Center; Jacob A. Sloane, MD PhD, Beth Israel Deaconess Medical Center; Jacob A. Sloane, MD PhD, Beth Israel Deaconess Medical Center
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Efficacy and Safety of Ocrelizumab in Relapsing Multiple Sclerosis: Results of the Phase III, Interferon ß-1a-Controlled OPERA I and OPERA II Studies
Fred Lublin, MD, Icahn School of Medicine at Mount Sinai; Douglas L Arnold, MD, NeuroRx Research; Amit Bar-Or, MD, FRCPC, McGill University; Giancarlo Comi, MD, University Vita-Salute San Raffaele; Stephen L Hauser, MD, University of California; Krzysztof Selmaj, MD, PhD, Medical University of Lodz; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Peter Chin, MD, Genentech, Inc.; Paulo Fontoura, MD, PhD, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Gaelle Klingelschmitt, MSc, F. Hoffmann-La Roche Ltd.; Donna Masterman, MD, Genentech, Inc.; Ludwig Kappos, MD, PhD, University Hospital Basel; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Heinrich-Heine-University Düsseldorf; Ashley J Porter, PhD, Articulate Science
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Effect of Ocrelizumab on Clinical Disability in Two Identical Phase III, Double-Blind, Double-Dummy, Interferon ß-1a–Controlled Studies
Fred Lublin, MD, Icahn School of Medicine at Mount Sinai; Douglas L Arnold, MD, NeuroRx Research; Amit Bar-Or, MD, FRCPC, McGill University; Giancarlo Comi, MD, University Vita-Salute San Raffaele; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Heinrich-Heine-University Düsseldorf; Stephen L Hauser, MD, University of California; Krzysztof Selmaj, MD, PhD, Medical University of Lodz; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Peter Chin, MD, Genentech, Inc.; Paulo Fontoura, MD, PhD, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Gaelle Klingelschmitt, MSc, F. Hoffmann-La Roche Ltd.; Donna Masterman, MD, Genentech, Inc.; Ludwig Kappos, MD, PhD, University Hospital Basel; Ashley J Porter, PhD, Articulate Science
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Relapse Rates of Patients with Multiple Sclerosis Newly Initiating Subcutaneous Interferon ß-1a vs Oral Disease-Modifying Drugs in the Real World
Chris M Kozma, PhD, CK Consulting Associates, LLC; Frederick Munschauer, MD, EMD Serono, Inc.; Amy L Phillips, PharmD, EMD Serono, Inc.; Michele Springer, BA, Caudex
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Effect of Oral Fingolimod Treatment on Brain Volume Loss in Patients with Relapsing–Remitting Multiple Sclerosis Estimated Using Bayesian Methodology
Guosheng Yin, PhD, The University of Hong Kong; Xiangyi Meng, PhD, Novartis Pharmaceuticals Corporation; M. Zahur Islam, PhD, Novartis Pharmaceuticals Corporation; Jeremy Bright, PhD, Oxford Pharmagenesis; Terence Smith, PhD, Oxford Pharmagenesis
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Oral Therapy Switches: How Many Patients Are Returning to Injectable Therapies?
Janet Moores, RN, BN, MBA, University of Calgary MS Clinic; Janet Moores, RN, BN, MBA, University of Calgary MS Clinic
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Methylprednisolone Treatment, Patient Reported Tolerance and Efficacy
Jeffrey B English, MD, Multiple Sclerosis Center of Atlanta; Sophia Strickland, pre-medical student, Multiple Sclerosis Center of Atlanta; Patrick J English, pre-business student, Multiple Sclerosis Center of Atlanta

Clinical Outcomes in Discontinuation and Restart of Natalizumab
Jeffrey B English, MD, Multiple Sclerosis Center of Atlanta; Debra K Johnson, RN, Multiple Sclerosis Center of Atlanta; Mitzi J. Williams, MD, Multiple Sclerosis Center of Atlanta; Donna M Court, MN, RN, Multiple Sclerosis Center of Atlanta

Global Reach Webinars Enrich Nursing Scope of Practice
Jennifer Smrtka, MSN, ARNP-BC, MSCN, University of Miami; Lori Mayer, DNP, MSN, RN, MSCN, MS Clinic of Central Texas/Central Texas Neurology Consultants
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Brain Health: Time Matters in Multiple Sclerosis – Developmental Process and Objectives of International Consensus Policy Recommendations
Kathleen Costello, MS, ANP-BC, MSCN, National Multiple Sclerosis Society; Helmut Butzkueven, MBBS, PhD, University of Melbourne; Suhayl Dhib-Jalbut, MD, RUTGERS Robert Wood Johnson Medical School; Jeremy Hobart, PhD FRCP, Plymouth University Peninsula Schools of Medicine and Dentistry; Gisela Kobelt, PhD, European Health Economics; George Pepper, ., Shift.ms; Maria Pia Sormani, PhD, University of Genoa; Christoph Thalheim, ., Patient Advocate in Multiple Sclerosis; Anthony Traboulsee, MD, FRCPC, University of British Colombia; Timothy Vollmer, MD, University of Colorado Denver; Gavin Giovannoni, MBBCh, PhD, Queen Mary University London, Blizard Institute, Barts and The London School of Medicine and Dentistry; Katharine Murkett, ., Oxford PharmaGenesis; Heather Lang, DPhil, Oxford PharmaGenesis
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Infusion-Related Reactions With Ocrelizumab in the Phase III Double-Blind, Double-Dummy, Interferon ß-1a-Controlled OPERA I and OPERA II Studies
Krzysztof Selmaj, MD, PhD, Medical University of Lodz; Douglas L Arnold, MD, McGill University; Amit Bar-Or, MD, FRCPC, McGill University; Giancarlo Comi, MD, University Vita-Salute San Raffaele; Hans-Peter Hartung, MD, FRCP, FAAN, FANA, Heinrich-Heine-University Düsseldorf; Stephen L Hauser, MD, University of California; Fred Lublin, MD, Icahn School of Medicine at Mount Sinai; Anthony Traboulsee, MD, FRCPC, University of British Columbia; Nicole Mairon, MD, F. Hoffmann-La Roche Ltd.; Peter Chin, MD, Genentech, Inc.; Paulo Fontoura, MD, PhD, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Gaelle Klingelschmitt, MSc, F. Hoffmann-La Roche Ltd.; Donna Masterman, MD, Genentech, Inc.; Ludwig Kappos, MD, PhD, University Hospital Basel; Ashley J Porter, PhD, Articulate Science
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A Phase III, Open-label Study to Evaluate the Effect of Ocrelizumab on Immune Responses in Patients With Relapsing Multiple Sclerosis
Laurie Millar, PhD, F. Hoffmann-La Roche Ltd.; Carrie Li, PhD, F. Hoffmann-La Roche Ltd.; Henry Bennett, BSc, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Ashley J Porter, PhD, Articulate Science
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Incidence of Infusion-Associated Reactions Decreases with Subsequent Courses of Alemtuzumab: 5-Year Data from the Care-MS Extension Study
Lori Mayer, DNP, MSN, RN, MSCN, Central Texas Neurology Consultants; Edward J. Fox, MD, PhD, Central Texas Neurology Consultants; Christopher LaGanke, MD, North Central Neurology Associates; Bhupendra Khatri, MD, Wheaton Franciscan Regional MS Center; Ann D Bass, MD, Neurology Center of San Antonio; David H Margolin, MD, PhD, Genzyme, a Sanofi company; Linda Kasten, MA, PROMETRIKA, LLC; Patricia A Pagnotta, ARNP, MSN, MSCN, CCRN, Neurology Associates, PA
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Lymphopenia in Multiple Sclerosis Patients Treated with Delayed-Release Dimethyl Fumarate: Analysis of 2 Electronic Health Record Databases in the US
Madé Wenten, PhD, MPH, Biogen; Teesta Soman, MD, MBA, Biogen; Cathy Lally, MSPH, Biogen; Maneesh Juneja, BSc, Biogen; Susan Eaton, MSPH, MT (ASCP), Biogen; Claudia Prada, MD, PhD, Biogen; Anne Dilley, BA, MPH, PhD, Biogen; Jim B Lewin, PharmD, Biogen
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Alemtuzumab Causes Significant, Transient, Post-Infusion Thrombocytopenia and Other Non-Autoimmune Cytopenias Following Initial and Subsequent Courses
Roochi S Ghodasara, MD, Advanced Neurosciences Institute; Madelyn B Rarick, BSN, Advanced Neurosciences Institute; Miranda C Mosley, BS, Advanced Neurosciences Institute; Rachel A Morgan, BA, Advanced Neurosciences Institute; S.R. Sparrow Smith, BS, MA, Advanced Neurosciences Institute; Laurel Kagan, NP, Advanced Neurosciences Institute; Daniel Kantor, MD, NeuroNexus Center - Novel Pharmaceutics Institute; Joy Derwenskus, DO, MS, Advanced Neurosciences Institute; Samuel F. Hunter, MD, PhD, Advanced Neurosciences Institute; Roochi S Ghodasara, MD, Advanced Neurosciences Institute
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Key Results from PREFERMS: Real-World Patient Retention and Outcomes on Fingolimod Versus Platform Injectable Disease-Modifying Therapies in Early Relapsing–Remitting MS
Mark Cascione, MD, Tampa Neurology Associates, South Tampa Multiple Sclerosis Center; Bruce AC Cree, MD, PhD, University of California San Francisco; Daniel Wynn, MD, Consultants in Neurology MS Center; Xiangyi Meng, PhD, Novartis Pharmaceuticals Corporation; Lesley Schofield, PhD, Novartis Pharmaceuticals Corporation; Nadia Tenenbaum, MD, Novartis Pharmaceuticals Corporation; Jeremy Bright, PhD, Oxford Pharmagenesis; Terence Smith, PhD, Oxford Pharmagenesis
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Final Outcomes from the Teriflunomide TOWER Extension Study: Up to 6 Years of Follow-up (Core Plus Extension) in Patients with Relapsing Forms of MS
Mark S Freedman, MD, University of Ottawa and the Ottawa Hospital Research Institute; Ludwig Kappos, MD, University Hospital Basel; Giancarlo Comi, MD, University Vita-Salute San Raffaele; Aaron E Miller, MD, Icahn School of Medicine at Mount Sinai; Jerry Wolinsky, MD, University of Texas Health Science Center at Houston; Karthinathan Thangavelu, PhD, Genzyme, a Sanofi company; Philippe Truffinet, MD, Genzyme, a Sanofi company; Myriam Benamor, MD, Genzyme, a Sanofi company; Pascal Rufi, MD, Genzyme, a Sanofi company; Paul O'Connor, MD, University of Toronto

JC Virus Antibody Seropositivity Index Decreases with Reduced Infusion Frequency in Natalizumab-Treated Multiple Sclerosis Patients
Michael A Mercurio, MD, Rush University Medical Center; Michael Y Ko, MD, Rush University Medical Center; Roumen Balabanov, MD, Rush University Multiple Sclerosis Center; Jennifer A Strong, MS, Rush University Multiple Sclerosis Center; Dusan Stefoski, MD, Rush University Medical Center
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A Retrospective Assessment of Real-World Discontinuation Rates in Patients with Multiple Sclerosis Treated with Delayed-Release Dimethyl Fumarate
Michelle A Allan, RN BA Nursing GCert MS, Monash Health; Lindsay Grant, B.Pharm, Monash Health; Michelle A Allan, RN BA Nursing GCert MS, Monash Health; Jim B Lewin, PharmD, Biogen
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Real-World Comparison of Relapse Rates in Multiple Sclerosis Patients Treated with Disease-Modifying Therapies
Aaron Boster, MD, OhioHealth Neurological Physicians; Jacqueline Nicholas, MD, MPH, Novartis Pharmaceutical Corporation; Ning Wu, Ph.D., Biogen; Wei-Shi Yeh, PhD, Biogen; Monica A Fay, PharmD, Biogen; Michael R Edwards, PhD, Biogen; Ming-Yi Huang, PhD, Biogen; Andrew Lee, PhD, Biogen; Ming-Yi Huang, PhD, Biogen; Jim B Lewin, PharmD, Biogen
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Assessing the Incidence of Elevation in Eosinophils with the Use of Dimethyl Fumarate in Multiple Sclerosis
Demetrios Konstas, MD, University of South Florida; Natalie K Moreo, MD, University of South Florida; Chetan P Gandhy, MD, University of South Florida; Michelle Lyman, MSII, University of South Florida College of Medicine; Doris Deng, MSII, University of South Florida College of Medicine; Robert Soares, BS, University of South Florida; Steven Aradi, MD, University of Pennslyvania Perelman School of Medicine; Derrick S Robertson, MD, University of South Florida; Derrick Robertson, MD, University of South Florida
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Assessing the Incidence of Lymphopenia with the Use of Dimethyl Fumarate in Multiple Sclerosis
Demetrios Konstas, MD, University of South Florida; Natalie K Moreo, MD, University of South Florida; Chetan P Gandhy, MD, University of South Florida; Doris Deng, MSII, University of South Florida College of Medicine; Michelle Lyman, MSII, University of South Florida College of Medicine; Robert Soares, BS, University of South Florida; Derrick S Robertson, MD, University of South Florida; Derrick Robertson, MD, University of South Florida
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The Use of Delayed-Release Dimethyl Fumarate in Routine Medical Practice in the Treatment of Multiple Sclerosis (ESTEEM): 6-Month Interim Analysis
Nicholas Everage, PhD, Biogen; Claudia Prada, MD, PhD, Biogen; Shifang Liu, PhD, Biogen; Konstantin Balashov, MD, PhD, FAAN, Robert Wood Johnson Medical School; Richard Macdonell, MD, FRACP, Austin Health, Univ. of Melbourne; Jörg Windsheimer, MD, Praxis für Neurologie und Psychiatrie; Kathryn Giles, MD, MSc, FRCPC, Cambridge Memorial Hospital; Jim B Lewin, PharmD, Biogen
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Lemtrada Infusion Experience: Neurology Infusion Vs Nonneurology Infusion Centers
Patricia A Pagnotta, ARNP, MSN, MSCN, CCRN, MS Center of Greater Orlando

Open-Label Phase III Extension Studies to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab in Relapsing MS and Primary Progressive MS
Robert Kuhelj, PhD, F. Hoffmann-La Roche Ltd.; Gurpreet Deol-Bhullar, BSc, OT, F. Hoffmann-La Roche Ltd.; Monika Garas, PhD, F. Hoffmann-La Roche Ltd.; Peter Chin, MD, Genentech, Inc.; Stephen L Hauser, MD, University of California; Xavier Montalban, MD, PhD, Hospital Vall d’Hebron University; Ashley J Porter, PhD, Articulate Science
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Serious Adverse Events, Autoimmunity, and Infections Following Alemtuzumab Therapy in a Large, High Disability, Treatment-Refractory MS Clinic Cohort
Roochi S Ghodasara, MD, Advanced Neurosciences Institute; Miranda C Mosley, BS, Advanced Neurosciences Institute; Rachel A Morgan, BA, Advanced Neurosciences Institute; S.R. Sparrow Smith, BS, MA, Advanced Neurosciences Institute; Madelyn B Rarick, BSN, Advanced Neurosciences Institute; Laurel Kagan, NP, Advanced Neurosciences Institute; Daniel Kantor, MD, Advanced Neurosciences Institute; Joy Derwenskus, DO, MS, Advanced Neurosciences Institute; Samuel F. Hunter, MD, PhD, NeuroNexus Center - Novel Pharmaceutics Institute; Roochi S Ghodasara, MD, Advanced Neurosciences Institute
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Long-Term Effect of Fingolimod on Disability: A Categorical Trend Analysis over 8 Years
Shannon Ritter, MS, Novartis Pharmaceuticals Corporation; Anthony T Reder, MD, University of Chicago; Daniela Piani Meier, PhD, Novartis Pharma AG; Davorka Tomic, PhD, Novartis Pharma AG; Bruce AC Cree, MD, PhD, University of California San Francisco; Jeremy Bright, PhD, Oxford Pharmagenesis; Terence Smith, PhD, Oxford Pharmagenesis
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Oligodendrogenesis Via a Small Molecule Therapy for Treating Multiple Sclerosis Patients
Steven H Nye, Ph.D., ENDECE Neural, LLC; James G Yarger, Ph.D., ENDECE Neural, LLC
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Alemtuzumab Infusion Experience
Tania A Reyna, MD, Oklahoma Medical Research Foundation; Tony Sharp, PA, Oklahoma Medical Research Foundation; Cecilie Fjeldstad, PhD, Oklahoma Medical Research Foundation; Jennifer Smith, PA, Oklahoma Medical Research Foundation; Gabriel Pardo, MD, Oklahoma Medical Research Foundation; Tania A Reyna, MD, Oklahoma Medical Research Foundation
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Treatment Adherence, Persistence, and Compliance at 96 Weeks in MS Patients Using Rebismart® for Injection of Interferon β-1a
Virginia Devonshire, MD, University of British Columbia; Anthony Feinstein, MPhil, PhD, FRCP, University of Toronto, Sunnybrook Health Sciences Centre; Alan Gillett, PhD, EMD Serono; Virginia Devonshire, MD, University of British Columbia

Infusion-Related Reactions in the Phase III Double-Blind, Placebo-Controlled ORATORIO Study of Ocrelizumab in Primary Progressive Multiple Sclerosis
Xavier Montalban, MD, PhD, Vall d'Hebron University Hospital; Douglas L Arnold, MD, McGill University; Amit Bar-Or, MD, FRCPC, McGill University; Jérôme de Seze, MD, PhD, University Hospital of Strasbourg; Gavin Giovannoni, MBBCh, PhD, FCP (Neurol., SA), FRCP, FRCPath, Queen Mary University of London; Bernhard Hemmer, MD, Munich Cluster for Systems Neurology (SyNergy); Kottil Rammohan, MD, University of Miami; Nicole Mairon, MD, F. Hoffmann-La Roche Ltd.; Peter Chin, MD, Genentech, Inc.; Paulo Fontoura, MD, PhD, F. Hoffmann-La Roche Ltd.; Hideki Garren, MD, PhD, F. Hoffmann-La Roche Ltd.; Donna Masterman, MD, Genentech, Inc.; Annette Sauter, MD, F. Hoffmann-La Roche Ltd.; Jerry Wolinsky, MD, University of Texas Health Science Center at Houston; Ashley J Porter, PhD, Articulate Science
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Cuprizone Mouse Model of Demyelination: Environmental Enhancement Reverses Cognitive Deficits
Zahra Almosawi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Amal Almahroos, Bsc, College of Medicine and Medical Sciences, Arabian Gulf University; Reem Abdulla, Bsc, College of Medicine and Medical Sciences, Arabian Gulf University; Ayman Mohamed, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Hawra Alalwan, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Ahmmed Almubarak, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Fajer Alammadi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University; Amer Kamal, Professor, College of Medicine and Medical Sciences, Arabian Gulf University; Ahmed Al-Mahrezi, BSc, College of Medicine and Medical Sciences, Arabian Gulf University
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